Specification :

Preparation, Dosage and Administration Cassia Senna.:
Senna leaf extract of Cassia angustifolia extract inch Name CAS No. 85187-05-9 EINECS ELINCS 286-092-5 Total Sennosides Senna leaf extract of Cassia acutifolia Infusion picture photo image: dry pods or leaves should be soaked in warm water for a 6-l2 hours. If they Alexandrian Senna Pods use 3-6 in a cup of water, if they Tinnevelly Senna, use 4-l2 pod. These names are given to two different species when sold commercially. Tincture: take 2-4ml of the tincture taken before bed.

Dosage and Administration:

1.5 ~ 3g for laxation, 5 ~ 10g for purification. This herb is soaked in boiling water for 5 minutes for oral administration.

Unless otherwise specified: 0.6 ~ 2.0 g ( corresponding to 20 ~ 30 mg hydroxyanthracene derivatives are calculated as sennoside B) per day cut or herb powder or dry extracts for teas, decoctions, cold macerates, or potions. Liquid or solid forms of special treatment for oral use.
Correct dose is the smallest dose needed to maintain the soft dirt.
Note: The administration must be smaller than the daily dose.
Leaf dry: 0.6 ~ 2.0 g.
Infusion or decoction: 0.6 ~ 2.0 g in 150 ml of hot water for 10 to 30 minutes.
Cold wet: 0.6 ~ 2.0 g in 150 ml of cold water for 10 to 12 hours, strain, then heat before drinking.
Fluidextract 1: 1 ( g / ml) : 0.6 ~ 2.0 ml.
Elixir: 0.6 ~ 2.0 ml fluidextract sweet.
Dry hydroalcoholic extract ( 5.5 ~ 8.0% glycosides hydroxyanthracene) : 0.25 ~ 0.55 g.
To use a laxative formula: extract 50mgs NMT in 24 hours.
Special caution for use: Stimulating laxatives must not be used for more than one to two weeks without medical advice.
Overdosage: Electrolyte and fluid imbalance.

Special warning: The use of stimulating laxatives for more than the recommended period can cause intestinal sluggishness.

This preparation should be used only if no effects can be obtained through a change in diet or use of bulk-forming products. Not indicated for: Children younger than age 12 years, pregnant and lactating women

Precautions:

Senna leaf and other stimulant laxatives should not be used for more than two weeks to four without the use or misuse of medical supervision.Chronic senna leaves can also cause electrolyte and fluid inbalances thus affecting the balance of your body.

Senna and other stimulant laxatives should not be used for more than two weeks to four without medical supervision. Using more than the recommended senna can cause lazy bowel syndrome and permanent damage to the intestinal lining. Chronic use or misuse can also cause electrolyte and fluid imbalances, which can have adverse effects on the heart. To prevent or treat constipation, most doctors recommend dietary changes or try a lighter, bulk-forming laxatives such as senna or psyllium before using other anthraquinone laxatives. approach involves eating a diet high fiber diet, drink six to eight glasses of water a day, and get plenty of regular exercise.

Unless otherwise stated by the physician, senna should not be used by anyone with intestinal obstruction, gastroenteritis, or intestinal inflammatory diseases such as Crohn' s disease, colitis, irritable bowel syndrome, or appendicitis. Senna also be avoided by those who are undiagnosed abdominal pain. Senna should not be used by children younger than age 12. Senna should not be used by pregnant or lactating women. This can significantly reduce drug absorption and reduce the efficiency of each drug over-the-counter or prescription. Children and seniors, who may be more susceptible to the effects of senna, should start with smaller doses of the herb.
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Safety:

Can cause cramping, so are best used in combination with other Herb' s. It should not be taken for more than two weeks to avoid weakening of the intestine. Should not be used if you suffer from diarrhea, diarrhea or abdominal pain. Consult with your doctor if you experience frequent diarrhea. If you are pregnant, nursing, taking medication that has a medical condition, consult your physician before using this product.

Bottom line: At present, it seems reasonable to conclude that short-term use of senna quite safe, while long-term use may or may not be safe. However, senna is not recommended for prolonged use. Chronic senna consumption can cause dependency, meaning that it becomes impossible to have a bowel movement without it. In addition, there are sporadic reports of unusual reactions to chronic use of senna, as hepatitis.Thus, if properly used, senna should be safe.

As with all laxatives, people with significant intestinal disease, such as ulcerative colitis, should not use senna.

If senna brought to the point of diarrhea, the body can be discharged from the mineral potassium. This is very dangerous for people using drugs in the family digoxin, which can cause dangerous cardiac arrythmias if sodium levels in the blood are inadequate. People who use medications that themselves deplete the body of potassium, such as thiazide or loop diuretics, are at risk of this particular complication of excessive senna.

The safety of senna during pregnancy has not been established, and pregnant women are advised to avoid senna during the first trimester.Nursing women should also avoid using senna.
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Toxicity:

Total acute toxicity Sennosides.LD50.Mice.Oral.1.414g/ kg.Reference: Zhong Xi Yi Jie He Za Zhi, 1986.6 ( 8) ; 455.by Ya Jin Cheng, etc.

Total Sennosides acute toxicity, lethal dose, 50 percent of deaths, LD50.Mice.Oral.1.414g/ kgs, the same as the basic raw 36.3g/ kg senna leaves, the dose is 300 times the human dose clinical, clinical toxicity study of the effect of senna leaves 102 cases, no toxic effects find.Reference: H. Wagner Drogen-analysis, 1983; 99

Side Effects:

In a single incident, discomfort such as cramps in the digestive tract. These cases require a dose reduction.

With chronic use or abuse: Disturbance of balance of electrolytes, especially potassium deficiency, albuminuria and hematuria. Pigment implantation into the intestinal mucosa ( pseudomelanosis coli) is not harmful and usually reverses on stopping the drug. Potassium deficiency can lead to cardiac dysfunction and muscle weakness, especially with the use of the same cardiac glycosides, diuretics, or corticosteroids.

Stimulant laxatives such as senna tend to have more side effects than other laxatives, so it is important to take the lowest effective dose. Side effects of senna include abdominal cramps, diarrhea, and gas, which can be severe if the herb is used more than recommended or in large quantities.

These problems can be avoided by reducing the dosage and adding other spices. More serious effects include fainting, dehydration and electrolyte disturbances such as low blood potassium, albuminuria, and hematuria. Potassium deficiency can cause muscle weakness and impaired heart function. Potassium levels may drop even further if senna is combined with cardiac glycoside medications, diuretics, or corticosteroids. People using diet pills or teas should be sure that if senna is the element they use the product of short-term ( one month or less) .
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Interactions:

Because of its potential impact on levels of potassium, senna should not be combined with anti-arrhythmic drugs, thiazide diuretics, steroids corticoadrenal, or licorice root without the supervision of a doctor.If you are using: digoxin, thiazide diuretics, or loop diuretics, This is especially important not too often senna.

Application:
Gastrointestinal conditions.
Severe constipation.
Laxatives.
Properties:
People in northern Africa and southwestern Asia have used senna as a laxative for centuries. This is considered a " cleansing" herb because of its cathartic effect. In addition, the leaves are sometimes made into a paste and applied to various skin diseases. Ringworm and acne both treated in this way.
Suggested Dose: Dry hydroalcoholic extract ( 5.5 ~ 8.0% glycosides hydroxyanthracene) : 0.25 ~ 0.55 g. For the use of laxative formula: NMT 50mgs extract in 24 carefully hours.Special for use: Stimulating laxatives must not be used for more than one to two weeks without medical advice.
Safety and Toxicity:
Warning: The mechanism of action anthranoids, however, is somewhat alarming: they seem to work primarily by damaging the cells lining the colon. 1 In general, cell damage may be a precursor to cancer, and on the basis of these concerns have been raised that senna can increase the risk of colon cancer.
The use of stimulating laxatives for more than the recommended period can cause intestinal sluggishness.Not indicated for: Children younger than age 12 years, pregnant and lactating women.
Scientific Name: Cassia Senna ( Cassia angustifolia or Cassia acutifolia)
Parts used: leaves and pots Senna
Latin name: Cassia angustifolia or Cassia acutifolia.
Latin: Folium Cassiae
Plant Family: Leguminosae

Common name: Alexandrian Senna, Cassia lenitiva, Cassia lanceolata, Cassia officinalis, East Indian Senna, Nubian Senna, Tinnevelly Senna, Cassia Senna, Senna, Rajavriksha, Fan xia ye, American senna, locust plant

He cleanse and purify the blood and cause fresh habits and life of the bush body.A with winged leaves, each consisting of six pairs of smaller leaves. Yellow flowers, produced in spikes a little long at the top of the branch, which is quite large and striped with red.